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Molecular mechanisms controlling chemokine receptor mrna stability

Objective

mRNA stability is a major checkpoint for the expression of certain chemokine receptors, affecting leukocyte recruitment in sites of infection, tumours and inflammatory diseases. The project aim is to investigate how CCR2mRNA half-life is regulated and how this influence CCR2 gene expression. mRNA stability is a major checkpoint for the expression of certain chemokine receptors, affecting leukocyte recruitment in sites of infection, tumours and inflammatory diseases. The project aim is to investigate how CCR2mRNA half-life is regulated and how this influence CCR2 gene expression.

Call for proposal

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Coordinator

MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH
Address
Via eritrea 62
20157 Milano
Italy

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EU contribution
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