Objective mRNA stability is a major checkpoint for the expression of certain chemokine receptors, affecting leukocyte recruitment in sites of infection, tumours and inflammatory diseases. The project aim is to investigate how CCR2mRNA half-life is regulated and how this influence CCR2 gene expression. mRNA stability is a major checkpoint for the expression of certain chemokine receptors, affecting leukocyte recruitment in sites of infection, tumours and inflammatory diseases. The project aim is to investigate how CCR2mRNA half-life is regulated and how this influence CCR2 gene expression. Fields of science medical and health scienceshealth sciencesinflammatory diseases Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Call for proposal Data not available Funding Scheme RGI - Research grants (individual fellowships) Coordinator MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH Address Via eritrea 62 20157 Milano Italy See on map EU contribution No data