Objective
Our aim is to link non-invasive imaging and nucleic acid biotechnology to create new in vivo imaging methods. Oligonucleotide ligands termed aptamers bind with high affinity biological targets and can be obtained from large combinatorial libraries. Modified aptamers engineered to resist degradation and target molecular markers of disease are thus promising candidates both as diagnostic tools and as therapeutic agents. Using non-invasive imaging procedures (PET) , we will evaluate in animal models of disease the potential of stable aptamers for diagnostic and therapy. This project merges 6 groups specialized in the following fields:
i) biologically-stable aptamer production (including a leading biotech company);
ii) study of biomarkers in animal disease models, and
iii) in vivo imaging methods. The major spin-off expected is the creation of generic methods for diagnosis and evaluation of new therapies.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
91405 ORSAY
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.