Objective
This proposal is designed to improve the management and understanding of craniofacial anomalies (CFA). Integration of previous networks established to investigate clinical care (Eurocleft.) and gene-environment interaction in early human development (ESF network) provides, for the first time in Europe, adequate clinical resources and multidisciplinary critical mass. The work includes:
1) a multicentre randomised control trial of surgery for orofacial clefting (OFC);
2) a multicentre population based case-parental triad study of the role of specific genes, gene-environment interaction and gene-gene interaction in the aetiology of OFC;
3) a chromosomal approach to the identification of candidate genes for OFC;
4) development of sensitive molecular diagnostic assay for mutations underlying monogenic CFA; and
5) an informatics resource to underpin the other work and provide a dynamic resource to disseminate findings, assist CFA researchers, and promote good practice in clinical services. The project will be integrated with, and provide leadership for, a proposed global effort in the treatment and prevention of CFA.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine surgery
- social sciences other social sciences development studies social developments
- natural sciences biological sciences genetics mutation
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
M15 6FH MANCHESTER
United Kingdom
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Participants (18)
20142 MILANO
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1026 BUDAPEST
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81108 BRATISLAVA
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413 45 GOETEBORG
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4002 PLOVDIV
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13419 TALLINN
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489031 BARAKALDO-VIZCAYA
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2900 HELLERUP
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6500 HB NIJMEGEN
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0027 OSLO
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4 DUBLIN
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44100 FERRARA
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1000 LJUBLJANA
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AB25 2ZD ABERDEEN
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1017 KOEBENHAVN K/COPENHAEGEN
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DD1 4HR DUNDEE
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00014 HELSINKI
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EH1 1HN Edinburgh
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