Objective A rational approach to focused adjuvant therapy is urgently needed in the management of patients suffering from the most common cancers; the ability to identify patients at high risk would enable most cost-effective use of the treatments available. This proposal assembles a collaborative effort from seven leading European cancer research laboratories to identify new prognostic marker sets based on a systematic exploration of tissue protease systems functionally involved in tumour progression. The partners will apply state of the art molecular biology to identify the most relevant novel proteases, before embarking upon their quantitative measurement in large collections of patient material. The clinical studies for assessment of prognostic significance will examine the prognostic significance of each marker and derive marker sets, which optimise prognostic power. Commercially attractive kits will be assembled for the new marker sets. Fields of science medical and health sciencesclinical medicineoncologynatural sciencesbiological sciencesmolecular biology Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator COPENHAGEN UNIVERSITY HOSPITAL Address Stransboulevarden 49 2100 Koepenhagen Denmark See on map EU contribution € 0,00 Participants (6) Sort alphabetically Sort by EU Contribution Expand all Collapse all CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE France EU contribution € 0,00 Address Rue laurent fries 1 67404 Illkirch graffenstaden See on map KAROLINSKA INSTITUTE Sweden EU contribution € 0,00 Address 9,doktorsringen 9 a 171 77 Stockholm See on map UNIVERSIDAD DE OVIEDO Spain EU contribution € 0,00 Address San francisco 1-5 33003 Oviedo See on map UNIVERSITA VITA-SALUTE SAN RAFFAELE Italy EU contribution € 0,00 Address Via olgettina 58 20132 Milano See on map UNIVERSITE DE LIEGE*ULG Belgium EU contribution € 0,00 Address Place du 20 aout 7 4000 Liege See on map University of East Anglia United Kingdom EU contribution € 0,00 Address University plain NR4 7TJ Norwich See on map
