The major objective of this proposal is developing tools for functional proteomics for analysis of the structure and properties of the gene products of bacteria, yeasts , plants animals and human organisms . The approach is based on the patented (by Quattromed Ltd) method of epitop-tagging of the proteins of interest with the purpose of fast and reliable purification, identification and detection of interactions of protein of interest with other components of the cell. Availability of such methods is absolute prerequisite for developing new medicines for treatment of infectious, acquired and inherited diseases of humans , animals and plants. We plan to develop a large family of manufacturable products for research laboratories and food industry dealing with the study of the structure and function of different gene products. The long-term application of the technology is the development of the epitop-tagged sensor-molecules for reliable and efficient tracking of transgenes in GMO.
Funding SchemeEAW - Exploratory awards