Objective
Whipple's disease (WD) is a rare, multifactorial disease, in which the bacterium Tropheryma whipplei causes infections in predisposed hosts. We plan to set up the first multidisciplinary consortium to improve our understanding of the interaction of host, agent and environment in this disorder. This includes a coordinated collection of different tissues from WD patients and controls, studies of host factors (characterizing the underlying immunogenetic defect) and of environmental factors (occurrence of T. whipplei). In order to improve diagnosis, microbiologic characterization of the agent will include studies of growth conditions (allowing antibiotic susceptibility testing) and sequencing of the bacillus. Prospective therapy studies aim to improve the current antibiotic therapy and to test beneficial effects of new supportive treatments. This should lead to a significant improvement of the patients' disease burden.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
66421 HOMBURG
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.