Analysis of large-scale chromatin modifications in the human interphase nucleus in response to interferon-gamma

Objective

To understand the transcriptional activation of MHC class II expression by IFN-gamma we examine the JAK/STAT pathway for large-scale chromatin modification. The Bare Lymphocyte Syndrome (BLS) can serve as a model to track down regulatory factors.

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

CANCER RESEARCH UK

Address

Lincoln's Inn Field 61
WC2A 3PX London
United Kingdom