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Analysis of large-scale chromatin modifications in the human interphase nucleus in response to interferon-gamma

Objective

To understand the transcriptional activation of MHC class II expression by IFN-gamma we examine the JAK/STAT pathway for large-scale chromatin modification. The Bare Lymphocyte Syndrome (BLS) can serve as a model to track down regulatory factors.

Coordinator

CANCER RESEARCH UK
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Lincoln's Inn Field 61
WC2A 3PX London
United Kingdom