Objective
As unicellular organisms, bacteria must match their metabolic activity to the requirements of the environment. This is achieved by regulatory networks that respond to intra-and extra-cellular signals by modulating gene expression. This proposal aims to generate new data on the regulation of gene expression in bacillus subtilis using state-of-the-art technologies for analysing the proteome and transcriptome. The information will be constructed, in silico, into a model of the global regulatory networks that result from interactions between individual regulatory circuits. It will make full use of bioinformatical and physical resources generated by the european bacillus community during previous sequencing and functional analysis projects. The data will provide new strategies for the identification of gene function and will provide clues to general stress mechanisms induced in pathogenic bacteria in response to infection. A major outcome will be an innovative transcriptional database, subscript, that is inter-linked to existing genomic, proteomic and phenotypic databases, to provide one of the most complete descriptions of living organism.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences computer and information sciences databases
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences genetics RNA transcriptomes
- natural sciences mathematics pure mathematics mathematical analysis functional analysis
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NE2 4HH Newcastle - Upon Tyne
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.