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Content archived on 2024-05-27

Homologous recombination in plants (PLANTREC)

Objective

Major advances have been made in knowledge of plant genomes and the recombination processes regulating their structure and integrity. However exploitation of this is limited by absence of methodology for the targeted, in site modification of plant genes and chromosomes. In plants the somatic homologous recombination machinery is overwhelmed by another recombination process (NHEJ) , which causes incoming DNA to insert at a random position in the genome, often accompanied by unwanted rearrangements. This is an important reason for questioning the safety of transgenic crops. We directly address these issues and 5 academic and 2 industrial research groups together aim to develop novel tools to obtain gene targeting in plants, based on a detailed understanding of recombination in plants. The groups will contribute considerable novel expertise and biological material to the project: plant hyperecombination mutants, cloned genes and proven assays.

Fields of science (EuroSciVoc)

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Topic(s)

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Call for proposal

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Funding Scheme

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CSC - Cost-sharing contracts

Coordinator

UNIVERSITÉ BLAISE PASCAL CLERMONT-FERRAND II
EU contribution
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Address
Avenue des Landais 24, Complexe Universitaire des
63177 AUBIERE
France

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Total cost

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Participants (7)

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