Objective
Major advances have been made in knowledge of plant genomes and the recombination processes regulating their structure and integrity. However exploitation of this is limited by absence of methodology for the targeted, in site modification of plant genes and chromosomes. In plants the somatic homologous recombination machinery is overwhelmed by another recombination process (NHEJ) , which causes incoming DNA to insert at a random position in the genome, often accompanied by unwanted rearrangements. This is an important reason for questioning the safety of transgenic crops. We directly address these issues and 5 academic and 2 industrial research groups together aim to develop novel tools to obtain gene targeting in plants, based on a detailed understanding of recombination in plants. The groups will contribute considerable novel expertise and biological material to the project: plant hyperecombination mutants, cloned genes and proven assays.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- natural sciencesbiological sciencesgeneticsDNA
- agricultural sciencesagriculture, forestry, and fisheriesagriculture
- natural sciencesbiological sciencesgeneticschromosomes
- natural sciencesbiological sciencesgeneticsgenomes
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Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
63177 AUBIERE
France