Objectif
The proposal concentrates on a central biomedical problem: the nature of the nerve cell changes underlying learning and memory. The objectives are to elucidate the molecular changes occurring in the coupling between nerve cells taking part in a learning process and lay the foundation for new ways to diagnose, prevent and possibly treat memory defects. The objectives will be achieved by using state of the art molecular and biological techniques to analyse a cellular model of learning - long term potentiation (LTP) in the belief that this general phenomenon represents a biological universal which is used by higher and lower animals during learning and memory processes. The proponent experts to detect principles for enhancing the efficiency of molecules (AMPA receptors) which are responsible for the impulse traffic between nerve cells engaging in thought processes. Increased insight may lead to improved prevention and treatment of memory difficulties.
Thème(s)
Appel à propositions
Data not availableRégime de financement
CSC - Cost-sharing contractsCoordinateur
0316 OSLO
Norvège