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Genes controlling neuronal specification and differentiation

Objective

The generation of different neuronal phenotypes during development is a prerequisite for the function of the nervous system. The present proposal is focused on the role of major transcriptional control genes that are involved invertebrate neuron specification and differentiation. We aim to understand how their expression is controlled and how they exert their function. The functional analysis will include the identification of their target genes and the characterisation of the genetic and cellular context required for their function. A further aim of the project is to begin to understand the molecular link between neuron generation and withdrawal from the cell cycle.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
Address
Deutschordenstrasse 46
60528 Frankfurt Am-main
Germany

Participants (5)

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
France
Address
Rue Laurent Fries 1
67404 Illkirch Graffenstaden
HELLENIC PASTEUR INSTITUTE
Greece
NATIONAL RESEARCH COUNCIL OF ITALY
Italy
Address
Viale Carlo Marx 15
00156 Roma
THE HEBREW UNIVERSITY OF JERUSALEM - THE AUTHORITY FOR RESEARCH AND DEVELOPMENT
Israel
Address
Givat Ram
91904 Jerusalem
UNIVERSITY OF EDINBURGH
United Kingdom
Address
Summerhall
EH9 1QH Edinburgh