Genes controlling neuronal specification and differentiation

Objective

The generation of different neuronal phenotypes during development is a prerequisite for the function of the nervous system. The present proposal is focused on the role of major transcriptional control genes that are involved invertebrate neuron specification and differentiation. We aim to understand how their expression is controlled and how they exert their function. The functional analysis will include the identification of their target genes and the characterisation of the genetic and cellular context required for their function. A further aim of the project is to begin to understand the molecular link between neuron generation and withdrawal from the cell cycle.

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-9. - Neurosciences

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

Address

Deutschordenstrasse 46
60528 Frankfurt Am-main
Germany

Participants (5)

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

France

Address

Rue Laurent Fries 1
67404 Illkirch Graffenstaden

HELLENIC PASTEUR INSTITUTE

Greece

NATIONAL RESEARCH COUNCIL OF ITALY

Italy

Address

Viale Carlo Marx 15
00156 Roma

THE HEBREW UNIVERSITY OF JERUSALEM - THE AUTHORITY FOR RESEARCH AND DEVELOPMENT

Israel

Address

Givat Ram
91904 Jerusalem

UNIVERSITY OF EDINBURGH

United Kingdom

Address

Summerhall
EH9 1QH Edinburgh