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Content archived on 2024-05-24

Assembly, maintenance and novel potential drug targets of the synapse (SYNAPTOGENET)

Objective

Synapses are key elements for neuronal communication in the brain. Many synaptic proteins are targets for neuropharmaceuticals as well as neurotoxins and street drugs. Synaptic dysfunction is associated with various neurological disorders. The pivotal objectives of this study are to gain precise insight into processes of synaptic assembly and function, to understand path mechanisms underlying synaptic dysfunction and to discover novel targets for neuropharmaceuticals. The skills of the partners in molecular biology, genetics (including advanced trans-genie technologies in mouse and fly), bio informatics, biochemistry, electro-physiology, cell biology and functional anatomy will be combined to: study mechanisms of synapse assembly, identify genes involved in acquisition of synaptic competence (i.e. the ability to form synapses), analyse molecular mechanisms of transmitter release, and find and validate new potential drug targets.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

LEIBNIZ-INSTITUT FUER NEUROBIOLOGIE
EU contribution
No data
Address
Brenneckestrasse 6
39118 MAGDEBURG
Germany

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (6)

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