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Content archived on 2024-05-24

Orexins / hypocretins - new targets for therapeutic control of feeding and sleeping disorders (OREXINS)

Objective

Since their discovery in 1998 two peptides named origins (synonym hypo cretins) receive much attention because of their central role in the regulation of basic body functions: food intake, energy balance and the sleep waking cycle. Loss of the origin containing neurons in the hypothalamus, which project widely in the brain, is the cause of human narcolepsy, a disabling disorder of vigilance, which also occurs in dogs where the G-protein coupled origin receptors are missing. Understanding the functions of this central command system on the molecular, cellular, network, behaviour and clinical levels is necessary for a rational therapeutic approach to disorders of feeding and sleeping. Our consortium representing molecular biology, physiology, pharmacology, biological psychology, clinical medicine and the pharmaceutical industry will take this task.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

Data not available

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

UNIVERSITAETSKLINIKUM DUESSELDORF
EU contribution
No data
Address
Universitaetstrasse 1
40001 DUESSELDORF
Germany

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (4)

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