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Content archived on 2024-05-27

Genetic mechanisms that determine neuronal progenitor identity in the ventral spinal cord (STEMBRIDGE)

Objective

The most remarkable feature of the Central Nervous System (CNS) is the massive array of neurons that permit the diversity of functional neuronal circuits. The spinal cord contains neurons that integrate and relay sensory information from the periphery to the brain and the neurons that control and co-ordinate motor output. Mature neurons derive from neuronal progenitors that appear in a highly patio-temporal order in different neural regions. A major question in developmental neurobiology is to understand how the developing neural tube becomes patterned into distinct clusters of neuronal progenitors. A second, equally important, issue is to define the genetic mechanisms that govern cell fate determination and subtype specification of cells in the same progenitor pool. The latter question is of important relevance to stem cell therapy for neurodegenerative disorders of the brain and spinal cord.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

CYPRUS INSTITUTE OF NEUROLOGY AND GENETICS
EU contribution
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Address
International Airport Avenue, No.6
1683 NICOSIA
Cyprus

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Total cost

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Participants (6)

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