Objective
With a prevalence of about 2%, mental retardation (MR) poses an important medical and socio-economic problem. The European MRX Consortium has been instrumental in characterizing families with non-specific X-linked MR (MRX) and cloning most of the MRX genes, with two objectives:
(1) increasing the possibilities for genetic counselling for MR (X) and
(2) elucidation of the neurobiological mechanisms underlying MR, to create a basis for therapeutic intervention. Using neuronal tissue cultures and genetically modified mice we will study the biological mechanisms which link MRX gene defects to deficient cognitive functioning in humans. In addition, cloning of additional MRX genes will be accelerated using highly innovative approaches. These studies will greatly enhance our understanding of the cellular basis of cognition.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
6500 HB NIJMEGEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.