The long duration of untreated illness in early psychosis calls for intensive efforts for early recognition and early intervention. EPOS is the first five-country prospective study designed to predict the transition to psychosis and the course of psychopathology and disability in persons with an increased risk of schizophrenia on the basis of a multi-level assessment including psychopathology, neurocognition, and brain imaging. Outcome is measured at 9 and 18-month follow-ups in order to establish a "risk profile". In addition, EPOS will study pathways and obstacles to care and calculate delays to adequate treatment. EPOS is also the first study of the course of disabilities and quality of life during programs of schizophrenia. Intervention (such as psychotherapy or medication) is monitored and outcome is assessed prospectively.
Funding SchemeCSC - Cost-sharing contracts
1105 BC Amsterdam
B6 5UG Birmingham
20520 Turku / Abo