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Involvement of PKCgamma in long-lasting hyperalgesia induced by optiate analgesics

Objective

Using both behavioural and cellular approaches on PKCgamma knockout/wild-type mice, this project will evaluate the contribution of this enzyme in the delayed effects of fentanyl (hyperalgesia, tolerance, withdrawal, psychoaffective effects and cognitive deficits), an opiate analgesic widely used in human surgery.

Topic(s)

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Call for proposal

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Coordinator

Universitat Pompeu Fabra
Address
C/ doctor aiguader 80
08003 Barcelona
Spain

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EU contribution
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Participants (1)