Involvement of PKCgamma in long-lasting hyperalgesia induced by optiate analgesics

Objective

Using both behavioural and cellular approaches on PKCgamma knockout/wild-type mice, this project will evaluate the contribution of this enzyme in the delayed effects of fentanyl (hyperalgesia, tolerance, withdrawal, psychoaffective effects and cognitive deficits), an opiate analgesic widely used in human surgery.

Fields of science

• medical and health sciences › clinical medicine › surgery
• natural sciences › biological sciences › biochemistry › biomolecules › proteins › enzymes

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

Data not available

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

Universitat Pompeu Fabra

Address

C/ Doctor Aiguader 80
08003 Barcelona
Spain

Participants (1)

Not available