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Content archived on 2024-05-24

New methodologies for assessing the potential of unintended effects in genetically modified food crops.

Objective

Market introduction of genetically modified (GM) food crops in Europe has given rise to broad public concern, which of a great deal is based on uncertainties related to safety for humans, animals and environment. One of the key issues in safety evaluation of GM plants is whether unexpected or unintended changes may have taken place in the organism due to genetic modification, that could affect its safety or nutritional status. It is recognised that adequate and effective methods to detect the sources of possible unintended effects do not exist, partly because little knowledge is available on the nature of genes involved in synthesis of natural toxins. The overall objective is to develop new methodology to assess risks from this possible food borne hazard. Emphasis is placed on the exploitation of innovative cell factory technologies (I.E. genomics, proteomics, metabolite profiling) to identify and/or eliminate potential hazardous metabolic perturbations in whole complex GM crop plants at the earliest step in the food chain. This will establish an improved and transparent risk assessment strategy for GM plants, reduces animal testing and will reassure consumers confidence in the supply of safe and nutritious novel foods

Fields of science (EuroSciVoc)

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Topic(s)

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