Objective The Lactic Acid Bacteria (LAB) is well known for their extensive use in the preparation of fermented food products. In addition, the potential health benefit they may exert in humans has been intensively investigated during the last century. However, the mechanisms underlying the health promoting traits attributed to LAB, especially lactobacilli, remain vastly unknown which has impaired the rational design of robotic screening methods with accurate predictive value. As the probioticarea corresponds to a rapidly expanding market, the DEPROHEALTH project first aims at establishing a correlation between inviter tests and mouse models mimicking important human intestinal disorders such as Inflammatory Bowel Disease, Helicobacter pylori and Rotavirus infections. As these diseases correspond to major public health problems, second generation probioticstrains with enhanced prophylactic or therapeutic properties will also be designed during the project. These designed strains and the isogonics parental ones will be used to unravel mechanisms involved in the immunomodulation capacity of specific Lactobacillus strains. Fields of science medical and health scienceshealth sciencespublic healthnatural scienceschemical sciencesorganic chemistryorganic acidsnatural sciencesbiological sciencesmicrobiologybacteriologymedical and health sciencesclinical medicinegastroenterologyinflammatory bowel disease Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-1. - Key action Food, Nutrition and Health Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator INSTITUT PASTEUR DE LILLE Address 1,rue du professeur calmette 1 59019 Lille France See on map EU contribution € 0,00 Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all BARTS & THE LONDON NHS TRUST United Kingdom EU contribution € 0,00 Address West smithfield EC1A 7BE London See on map CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Spain EU contribution € 0,00 Address S/n,poligono de la coma s/n 46980 Campamento/paterna See on map FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY VZW Belgium EU contribution € 0,00 Address 35,ledeganckstraat 35 9000 Gent See on map RHODIA FOOD SAS France EU contribution € 0,00 Address Quai paul-doumer 25 92408 Courbevoie See on map UNIVERSITAT DE VALENCIA Spain EU contribution € 0,00 Address Avda. blasco ibaçez 17 46071 Valencia See on map UNIVERSITE CATHOLIQUE DE LOUVAIN Belgium EU contribution € 0,00 Address Croix du sud 5 1348 Louvain-la-neuve See on map UNIVERSITY OF NEW SOUTH WALES Australia EU contribution € 0,00 Address 2052 University of new south See on map UNIVERSITÀ DEGLI STUDI DI SIENA Italy EU contribution € 0,00 Address Viale bracci policlinico dellle scotte 53100 Siena See on map
