Alcohol related cancers and genetic susceptibility in europe

Objective

Each year there are approximately 80,000 cases and 40,000 deaths of cancer of the upper aero-digestive tract (UADTI in the 15 European Union (EU) countries, making it the fourth most common cancer in the EU. The proposed study will recruit over 2500 cases of UADT cancers and a group of comparable controls in 9 centres of the EU. It will test specific hypotheses including genetic susceptibility to alcohol metabolisation, patterns of alcohol consumption and types of alcohol beverage, and dietary factors including low consumption of fruits and vegetables. Subsequently, it will investigate why some countries have incidence rates over 4 times greater than other countries. By incorporating information on genetic susceptibility, alcohol, dietary and other lifestyle patterns, the study will aim to identify individuals at a very high risk of developing UADT cancers.

Fields of science

• engineering and technology › other engineering and technologies › food technology
• agricultural sciences › agriculture, forestry, and fisheries › agriculture › horticulture › fruit growing
• medical and health sciences › clinical medicine › oncology
• agricultural sciences › agriculture, forestry, and fisheries › agriculture › horticulture › vegetable growing
• natural sciences › chemical sciences › organic chemistry › alcohols

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-1. - Key action Food, Nutrition and Health

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

INTERNATIONAL AGENCY FOR RESEARCH ON CANCER

Address

150,cours Albert Thomas 150
69372 Lyon
France

Participants (14)

CENTRO DI RIFERIMENTO ONCOLOGICO

Italy

Address

Via Pedemontana Occidentale 12
33081 Aviano

CHARLES UNIVERSITY PRAGUE

Czechia

Address

Studnokova 7
128 00 Praha 2

ESTONIAN BIOCENTRE

Estonia

Address

Riia St. 23
51010 Tartu

INSTITUT CATALA D'ONCOLOGIA

Spain

Address

Avenida Gran Via Km 2.7
08907 Hospitalet Del Llobregat

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

Address

Rue Camille Desmoulins 39, Institut Gustave Roussy
94805 Villejuif

KREFTREGISTERED, INSTITUTE OF POPULATION BASED CANCER RESEARCH

Norway

Address

Montebello
0310 Oslo

NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS

Greece

Address

Mikras Asias Street 75
11527 Athens

THE COMMON SERVICES AGENCY

United Kingdom

Address

South Trinity Road Trinity Park House
EH5 3SQ Edinburgh

THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN HEREINAFTER TRINITY COLLEGE DUBLIN

Ireland

Address

Trinity College
2 Dublin

UNIVERSITA DEGLI STUDI DI PADOVA

Italy

Address

Via 8 Febbraio, 2
Padova

Links

UNIVERSITAET BREMEN

Germany

Address

Bibliothekstrasse 1
28334 Bremen

UNIVERSITY OF MANCHESTER

United Kingdom

Address

Oxford Road
M13 9PL Manchester

UNIVERSITY OF NEWCASTLE UPON TYNE

United Kingdom

Address

NE1 7RU Newcastle Upon Tyne

UNIVERSITY OF TORINO

Italy

Address

Strada Provinciale 142
10060 Airasca