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Alcohol related cancers and genetic susceptibility in europe

Objective

Each year there are approximately 80,000 cases and 40,000 deaths of cancer of the upper aero-digestive tract (UADTI in the 15 European Union (EU) countries, making it the fourth most common cancer in the EU. The proposed study will recruit over 2500 cases of UADT cancers and a group of comparable controls in 9 centres of the EU. It will test specific hypotheses including genetic susceptibility to alcohol metabolisation, patterns of alcohol consumption and types of alcohol beverage, and dietary factors including low consumption of fruits and vegetables. Subsequently, it will investigate why some countries have incidence rates over 4 times greater than other countries. By incorporating information on genetic susceptibility, alcohol, dietary and other lifestyle patterns, the study will aim to identify individuals at a very high risk of developing UADT cancers.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

INTERNATIONAL AGENCY FOR RESEARCH ON CANCER
Address
150,Cours Albert Thomas 150
69372 Lyon
France

Participants (14)

CENTRO DI RIFERIMENTO ONCOLOGICO
Italy
Address
Via Pedemontana Occidentale 12
33081 Aviano
CHARLES UNIVERSITY PRAGUE
Czechia
Address
Studnokova 7
128 00 Praha 2
ESTONIAN BIOCENTRE
Estonia
Address
Riia St. 23
51010 Tartu
INSTITUT CATALA D'ONCOLOGIA
Spain
Address
Avenida Gran Via Km 2.7
08907 Hospitalet Del Llobregat
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Address
Rue Camille Desmoulins 39, Institut Gustave Roussy
94805 Villejuif
KREFTREGISTERED, INSTITUTE OF POPULATION BASED CANCER RESEARCH
Norway
Address
Montebello
0310 Oslo
NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS
Greece
Address
Mikras Asias Street 75
11527 Athens
THE COMMON SERVICES AGENCY
United Kingdom
Address
South Trinity Road Trinity Park House
EH5 3SQ Edinburgh
THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN HEREINAFTER TRINITY COLLEGE DUBLIN
Ireland
Address
Trinity College
2 Dublin
UNIVERSITA DEGLI STUDI DI PADOVA
Italy
Address
Via 8 Febbraio, 2
Padova
UNIVERSITAET BREMEN
Germany
Address
Bibliothekstrasse 1
28334 Bremen
UNIVERSITY OF MANCHESTER
United Kingdom
Address
Oxford Road
M13 9PL Manchester
UNIVERSITY OF NEWCASTLE UPON TYNE
United Kingdom
Address

NE1 7RU Newcastle Upon Tyne
UNIVERSITY OF TORINO
Italy
Address
Strada Provinciale 142
10060 Airasca