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Alcohol related cancers and genetic susceptibility in europe

Objective

Each year there are approximately 80,000 cases and 40,000 deaths of cancer of the upper aero-digestive tract (UADTI in the 15 European Union (EU) countries, making it the fourth most common cancer in the EU. The proposed study will recruit over 2500 cases of UADT cancers and a group of comparable controls in 9 centres of the EU. It will test specific hypotheses including genetic susceptibility to alcohol metabolisation, patterns of alcohol consumption and types of alcohol beverage, and dietary factors including low consumption of fruits and vegetables. Subsequently, it will investigate why some countries have incidence rates over 4 times greater than other countries. By incorporating information on genetic susceptibility, alcohol, dietary and other lifestyle patterns, the study will aim to identify individuals at a very high risk of developing UADT cancers.

Call for proposal

Data not available

Coordinator

INTERNATIONAL AGENCY FOR RESEARCH ON CANCER
Address
150,cours albert thomas 150
69372 Lyon
France

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EU contribution
No data

Participants (14)