Objective
This project will study basic inmunopathological mechanisms, including cellular and cytokine profiles, related to intraperitoneal immune granulomas seen in vaccinated farmed fish Atlantic salmon, rainbow trout and sea bass following the use of oil-adjuvant vaccines containing Aromas salmonicida, Vibrato angular or Pasteur Ella viscid. Emphasis on the contribution of eosinophilic granular cells/mast cells and of pro-inflammatory mediators and cytokines to granule formation. Techniques ranging from histocytoschemistry to gene expressions studies and ex vivo tissue explants will be used. Results contributing to the development of safer vaccine formulations for fish are expected.
The project has shed light on the underlying mechanisms of granuloma formation in vaccinated farmed fish and it has been documented that the characteristics of the vaccine formulation, e.g. extracellular products, antigen content and stability has a bearing on the extent of injection site reactions. It has been shown that different cytokines are produced at the site of injection and that it is also up-regulated in immunocompetent organs like the spleen a few days after vaccination.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
0033 OSLO
Norway
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.