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The development of vaccines to prevent shigella infections

Objective

Shigellosis is responsible for around 1 million deaths worldwide each year, and as yet there is no effective vaccine to present this disease. We intend to develop a new generation of shigella vaccines. This will be achieved by learning lessons from the limitations of current vaccine candidates, and extending our knowledge of pathogenesis and of the detailed structure of potential vaccine targets. We will then use novel methods to present and deliver antigens to the immune system , and identify the best vaccine candidates for subsequent clinical trials.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

N/A

Participants (4)

INSTITUT PASTEUR
France
Address
Rue Du Docteur Roux 25
75724 Paris
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
Address
University Offices, Wellington Square
Oxford
UNIVERSITY OF ROME "LA SAPIENZA"
Italy
Address
Piazzale Aldo Moro 5
00185 Roma
Universite Libre de Bruxelles
Belgium
Address
Avenue Franklin Roosevelt 50
Bruxelles