The development of vaccines to prevent shigella infections

Objective

Shigellosis is responsible for around 1 million deaths worldwide each year, and as yet there is no effective vaccine to present this disease. We intend to develop a new generation of shigella vaccines. This will be achieved by learning lessons from the limitations of current vaccine candidates, and extending our knowledge of pathogenesis and of the detailed structure of potential vaccine targets. We will then use novel methods to present and deliver antigens to the immune system , and identify the best vaccine candidates for subsequent clinical trials.

Fields of science

• medical and health sciences › basic medicine › immunology
• medical and health sciences › basic medicine › pharmacology and pharmacy › pharmaceutical drugs › vaccines

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-2. - Key action Control of Infectious Diseases

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

N/A

Participants (4)

INSTITUT PASTEUR

France

Address

Rue Du Docteur Roux 25
75724 Paris

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

United Kingdom

Address

University Offices, Wellington Square
Oxford

Links

UNIVERSITY OF ROME "LA SAPIENZA"

Italy

Address

Piazzale Aldo Moro 5
00185 Roma

Universite Libre de Bruxelles

Belgium

Address

Avenue Franklin Roosevelt 50
Bruxelles

Links