Effects of antibodies on hepatits c virus (hcv) antigen presentation to cd4 t cells: shaping of the t cell repertoire in chronic hcv infection

Objective

Chronic infection with the hepatits C virus (HCV) is characterised by high antibody titers against HCV proteins. We want to test if these antibodies can alter antigen processing, change the range of available T cell epitopes and thus shape the clonal composition of the HCV-specific T cell repertoire

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-2. - Key action Control of Infectious Diseases

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

CHIRON S.R.L.

Address

Via Fiorentina 1
53100 Siena
Italy