European resistance intervention study - reducing resistance in respiratory tract pathogens in children

Objective

The aim of this research proposal is to introduce and test the efficacy of intervention strategies by which the prevalence of resistant strains of Streptococcus pneumonia colonizing children attending Decks could be reduced. Since this paediatric flora is the major reservoir of these dangerous pathogens it is expected that a successful intervention at the level of the ecological reservoir will also have major impact on the prevalence of pneumococcal infections by resistant strains both in paediatric and adult disease. Five centres each located in a different country will carry out the interventions and strain collections. Four additional collaborating units will assist as reference centres for the harmonization of methods in clinical microbiology; molecular epidemiology of drug resistance genes and clones; data management and mathematical modelling (including risk assessment) of epidemiological aspects of EURIS.

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-2. - Key action Control of Infectious Diseases

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA

Address

Avenida Da Republica, Estacao Agronomica Nacional
Oeiras
Portugal

Participants (6)

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

Address

Rue De Tolbiac, 101
75654 Paris

INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA

Portugal

Address

Quinta Do Marques
2780-901 Oeiras

NATIONAL UNIVERSITY HOSPITAL

Iceland

Address

Eiriksgata 5
101 Reykjavik

SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL

Sweden

Address

Nobels Vaeg 18
Solna

TECHNISCHE UNIVERSITAET KAISERSLAUTERN

Germany

Address

Erwin Schroedinger Strasse 46
67663 Kaiserslautern

THE ROCKEFELLER UNIVERSITY

United States

Address

York Avenue 1230
10021-6399 New York