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European resistance intervention study - reducing resistance in respiratory tract pathogens in children

Objective

The aim of this research proposal is to introduce and test the efficacy of intervention strategies by which the prevalence of resistant strains of Streptococcus pneumonia colonizing children attending Decks could be reduced. Since this paediatric flora is the major reservoir of these dangerous pathogens it is expected that a successful intervention at the level of the ecological reservoir will also have major impact on the prevalence of pneumococcal infections by resistant strains both in paediatric and adult disease. Five centres each located in a different country will carry out the interventions and strain collections. Four additional collaborating units will assist as reference centres for the harmonization of methods in clinical microbiology; molecular epidemiology of drug resistance genes and clones; data management and mathematical modelling (including risk assessment) of epidemiological aspects of EURIS.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA
Address
Avenida Da Republica, Estacao Agronomica Nacional
Oeiras
Portugal

Participants (6)

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Address
Rue De Tolbiac, 101
75654 Paris
INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA
Portugal
Address
Quinta Do Marques
2780-901 Oeiras
NATIONAL UNIVERSITY HOSPITAL
Iceland
Address
Eiriksgata 5
101 Reykjavik
SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL
Sweden
Address
Nobels Vaeg 18
Solna
TECHNISCHE UNIVERSITAET KAISERSLAUTERN
Germany
Address
Erwin Schroedinger Strasse 46
67663 Kaiserslautern
THE ROCKEFELLER UNIVERSITY
United States
Address
York Avenue 1230
10021-6399 New York