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Content archived on 2024-05-27

Comparative analysis of proteome modulation in human pathogenic bacteria for the identification of new vaccines, diagnostics and antibacterial drug targets

Objective

This network intends to coordinate a group of laboratories interested in proteomicanalysis of pathogenic bacteria using advanced HTS technology, and focussing on the comparison of proteases expressed in physiologically relevant conditions .Comparative analysis of proteases expressed by fully sequenced genomes, and parallel transcript analysis with whole-genome DNA micro arrays , are expected to identify sets of proteins which are surface exposed or used by the bacteria to establish infection, or counteract host immunological defences. Such proteins are obvious candidates for vaccine, diagnostics, or antibacterial drugdevelopment.Pilot studies performed on a panel of selected human pathogens will be conducted in a coordinated manner , adopting common standards. To facilitate comparative studies the data obtained in different laboratories will be collected in a common format, and eventually collected in a newly designed database.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

THN - Thematic network contracts

Coordinator

CHIRON S.R.L.
EU contribution
No data
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (9)

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