Objective
Hepatitis B virus (HBV) chronic infection still poses a major health problem for Europe. The emergence of HBV variants will compound the problem if they are allowed to spread, leading to vaccine escape and chemotherapeutic failure. To prevent this, our collaborative study will: develop high throughput procedures for detecting these variants in patients from different parts of Europe; evaluate their immune escape and drug resistance phenotypes through the use of conventional and new cell culture and animal models; and establish quantification assays to monitor the dynamic of HBV variants during therapy. Our findings should lead to re-design of diagnostic assays, and of vaccine and therapeutic formulations, and to guidelines to biologists and clinicians for better prevention and treatment strategies. They should result in the reduction of HBV transmission and of severe liver disease in chronically infected patients.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology virology
- medical and health sciences health sciences infectious diseases DNA viruses hepatitis B
- medical and health sciences basic medicine pharmacology and pharmacy drug resistance
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- medical and health sciences clinical medicine hepatology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
69424 LYON
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.