The european network for vertically acquired hepatitis c virus infection (EPHN)

Objective

The EPHN is based on 39 reference centres for HCV infection in pregnant women and their children in 9 European countries. Obstetricians, paediatricians, and experts in virology, immunology, and epidemiology will pool data and expertise to resolve some still unanswered questions on the issue. HCV infected women enrolled at or before delivery and their children will be followed up prospectively to collect clinical and laboratory information (>500 pairs already enrolled). 100 previously identified vertically infected children will also be followed prospectively. This study will allow us to precisely define the risk of vertical HCV infection, timing and correlates of transmission, such as viral load and mode of delivery, the natural history of HCV infection in children, including extra hepatic manifestations, and the identification of early prognostic markers, such as cytokine production and HLA polymorphisms.

Fields of science

• humanities › history and archaeology › history
• natural sciences › biological sciences › microbiology › virology
• medical and health sciences › health sciences › public health › epidemiology
• medical and health sciences › health sciences › infectious diseases › RNA viruses › hepatitis C
• medical and health sciences › basic medicine › immunology

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-2. - Key action Control of Infectious Diseases

Call for proposal

Data not available

Funding Scheme

CON - Coordination of research actions

Coordinator

UNIVERSITY OF TORINO

Address

Piazza Polonia 94
10126 Torino (Turin)
Italy

Participants (42)

ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM

Netherlands

Address

Meibergdreef 9
1105 A2 Amsterdam

AZIENDA OSPEDALIERA - POLO UNIVERSITARIO L. SACCO

Italy

Address

Via Grassi 74
20157 Milano

AZIENDA OSPEDALIERA AUTONOMA - SANT'ANNA - O.I.R.M. TORINO

Italy

Address

Via Ventimiglia
10126 Torino (Turin)

CENTRAL HOSITAL AKERSHUS

Norway

Address

1474 Nordbyhagen

CENTRE HOSPITALIER UNIVERSITAIRE SAINT-PIERRE

Belgium

Address

Rue Haute 322
1000 Bruxelles

COMPLEJO HOSPITALARIO DONOSTIA

Spain

Address

Paseo Del Dr. Beguiristain S/n
20014 San Sebastian

HOSPITAL CLINICO SAN CECILIO

Spain

Address

Avenida Dr. Oloriz 16
18012 Granada

HOSPITAL DEL MAR

Spain

Address

Passeig Maritim 25-29
08003 Barcelona

HOSPITAL UNIVERSITARIO DE LA FE SEVASA

Spain

Address

Avenida De Campanar 21
46009 Valencia

HOSPITAL UNIVERSITARIO DOCE DE OCTUBRE

Spain

Address

Avenida De Cordoba
28041 Madrid

HOSPITAL UNIVERSITARIO DOCE DE OCTUBRE

Spain

Address

Avenida De Cordoba
28041 Madrid

HUMBOLDT-UNIVERSITAET BERLIN

Germany

Address

Augustenburger Platz 1
13353 Berlin

IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE

United Kingdom

Address

Norfolk Place
W2 1PG London

INSTITUT CATALA DE LA SALUT

Spain

Address

Paseo Valle De Hebron 119-129
08035 Barcelona

INSTITUT CATALA DE LA SALUT

Spain

Address

Paseo Valle De Hebron 119-129
08035 Barcelona

INSTITUTE OF HEALTH CARLOS III

Spain

Address

Calle Sinesio Delgardo 12
28020 Madrid

KAROLINSKA INSTITUTE

Sweden

Address

Huddinge University Hospital
141 86 Huddinge

KING'S HEALTHCARE TRUST

United Kingdom

Address

Denmark Hill, King's College Hospital
SE5 9RS London

NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS

Greece

Address

Mikras Asias Street 75
11527 Athens

OSPEDALE SANTA CHIARA DI TRENTO

Italy

Address

Largo Medaglie D'oro
38100 Trento

OUR LADY'S HOSPITAL FOR SICK CHILDREN

Ireland

Address

Crumlin
12 Dublin

PAEDIATRIC HOSPITAL BAMBINO GESU

Italy

Address

Piazza Sant'onofrio 4
00165 Roma

ROYAL HOSPITAL FOR SICK CHILDREN

United Kingdom

Address

Chalmers Crescent 10
EH9 1TS Edinburgh

SALHGRENSKA UNIVERSITY HOSPITAL

Sweden

Address

41685 Goeteborg

SONDURETA HOSPITAL

Spain

Address

Andrea Doria 55
07015 Palma De Mallorca

THE UNIVERSITY OF MILANO

Italy

Address

Via C. Pascal 38
20133 Milano

THE UNIVERSITY OF MILANO

Italy

Address

Via G. Grassi, 74
20157 Milano

UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE 'AMEDEO AVOGADRO'

Italy

Address

Corso Mazzini 18
28100 Novara

UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II

Italy

Address

Via S. Pansini 5
80131 Napoli

UNIVERSITA DEGLI STUDI DI PADOVA

Italy

Address

Via Gustiniani 3
35128 Padova

UNIVERSITA DEGLI STUDI DI PAVIA

Italy

Address

Viale Taramelli 5, Policlinico San Matteo
27100 Pavia

UNIVERSITAT DE BARCELONA

Spain

Address

Pass. Sant Joan De Deu 2
08950 Esplugues De Llobegrat

UNIVERSITY MEDICAL CENTRE UTRECHT

Netherlands

Address

Heidelberglaan 100
3584CX Utrecht

UNIVERSITY OF BOLOGNA

Italy

Address

Via Massarenti 11
40138 Bologna

UNIVERSITY OF CAGLIARI

Italy

Address

Via Ospedale 119
09100 Cagliari

UNIVERSITY OF GENOVA

Italy

Address

Largo G.gaslini 5
16147 Genova

UNIVERSITY OF GENOVA

Italy

Address

Largo R.benzi 10
16132 Genova

UNIVERSITY OF HAMBURG

Germany

Address

Martinistrasse 52
20246 Hamburg

UNIVERSITY OF ROME "LA SAPIENZA"

Italy

Address

Viale Dell'università 37 Policlinico Umberto I
00186 Roma

UNIVERSITY OF TORINO

Italy

Address

Via Ventimiglia 2
10126 Torino (Turin)

UNIVERSITÀ DEGLI STUDI DI TRIESTE

Italy

Address

Via Dell'istria 65/l
34137 Trieste

Università degli Studi di Napoli 'Federico II'

Italy

Address

Corso Umberto I 34
80138 Napoli

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