Objective
The EPHN is based on 39 reference centres for HCV infection in pregnant women and their children in 9 European countries. Obstetricians, paediatricians, and experts in virology, immunology, and epidemiology will pool data and expertise to resolve some still unanswered questions on the issue. HCV infected women enrolled at or before delivery and their children will be followed up prospectively to collect clinical and laboratory information (>500 pairs already enrolled). 100 previously identified vertically infected children will also be followed prospectively. This study will allow us to precisely define the risk of vertical HCV infection, timing and correlates of transmission, such as viral load and mode of delivery, the natural history of HCV infection in children, including extra hepatic manifestations, and the identification of early prognostic markers, such as cytokine production and HLA polymorphisms.
Funding Scheme
CON - Coordination of research actionsCoordinator
10126 Torino (Turin)
Italy
Participants (42)
1105 A2 Amsterdam
20157 Milano
10126 Torino (Turin)
1474 Nordbyhagen
1000 Bruxelles
20014 San Sebastian
18012 Granada
08003 Barcelona
46009 Valencia
28041 Madrid
28041 Madrid
13353 Berlin
W2 1PG London
08035 Barcelona
08035 Barcelona
28020 Madrid
141 86 Huddinge
SE5 9RS London
11527 Athens
38100 Trento
12 Dublin
00165 Roma
EH9 1TS Edinburgh
41685 Goeteborg
07015 Palma De Mallorca
20133 Milano
20157 Milano
28100 Novara
80131 Napoli
35128 Padova
27100 Pavia
08950 Esplugues De Llobegrat
3584CX Utrecht
40138 Bologna
09100 Cagliari
16147 Genova
16132 Genova
20246 Hamburg
00186 Roma
10126 Torino (Turin)
34137 Trieste
80138 Napoli