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Content archived on 2024-06-17

The european network for vertically acquired hepatitis c virus infection (EPHN)

Objective

The EPHN is based on 39 reference centres for HCV infection in pregnant women and their children in 9 European countries. Obstetricians, paediatricians, and experts in virology, immunology, and epidemiology will pool data and expertise to resolve some still unanswered questions on the issue. HCV infected women enrolled at or before delivery and their children will be followed up prospectively to collect clinical and laboratory information (>500 pairs already enrolled). 100 previously identified vertically infected children will also be followed prospectively. This study will allow us to precisely define the risk of vertical HCV infection, timing and correlates of transmission, such as viral load and mode of delivery, the natural history of HCV infection in children, including extra hepatic manifestations, and the identification of early prognostic markers, such as cytokine production and HLA polymorphisms.

Call for proposal

Data not available

Coordinator

UNIVERSITY OF TORINO
EU contribution
No data
Address
Piazza Polonia 94
10126 TORINO (TURIN)
Italy

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Total cost
No data

Participants (42)