Skip to main content

The european network for vertically acquired hepatitis c virus infection (EPHN)

Objective

The EPHN is based on 39 reference centres for HCV infection in pregnant women and their children in 9 European countries. Obstetricians, paediatricians, and experts in virology, immunology, and epidemiology will pool data and expertise to resolve some still unanswered questions on the issue. HCV infected women enrolled at or before delivery and their children will be followed up prospectively to collect clinical and laboratory information (>500 pairs already enrolled). 100 previously identified vertically infected children will also be followed prospectively. This study will allow us to precisely define the risk of vertical HCV infection, timing and correlates of transmission, such as viral load and mode of delivery, the natural history of HCV infection in children, including extra hepatic manifestations, and the identification of early prognostic markers, such as cytokine production and HLA polymorphisms.

Funding Scheme

CON - Coordination of research actions

Coordinator

UNIVERSITY OF TORINO
Address
Piazza Polonia 94
10126 Torino (Turin)
Italy

Participants (42)

ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
Address
Meibergdreef 9
1105 A2 Amsterdam
AZIENDA OSPEDALIERA - POLO UNIVERSITARIO L. SACCO
Italy
Address
Via Grassi 74
20157 Milano
AZIENDA OSPEDALIERA AUTONOMA - SANT'ANNA - O.I.R.M. TORINO
Italy
Address
Via Ventimiglia
10126 Torino (Turin)
CENTRAL HOSITAL AKERSHUS
Norway
Address

1474 Nordbyhagen
CENTRE HOSPITALIER UNIVERSITAIRE SAINT-PIERRE
Belgium
Address
Rue Haute 322
1000 Bruxelles
COMPLEJO HOSPITALARIO DONOSTIA
Spain
Address
Paseo Del Dr. Beguiristain S/n
20014 San Sebastian
HOSPITAL CLINICO SAN CECILIO
Spain
Address
Avenida Dr. Oloriz 16
18012 Granada
HOSPITAL DEL MAR
Spain
Address
Passeig Maritim 25-29
08003 Barcelona
HOSPITAL UNIVERSITARIO DE LA FE SEVASA
Spain
Address
Avenida De Campanar 21
46009 Valencia
HOSPITAL UNIVERSITARIO DOCE DE OCTUBRE
Spain
Address
Avenida De Cordoba
28041 Madrid
HOSPITAL UNIVERSITARIO DOCE DE OCTUBRE
Spain
Address
Avenida De Cordoba
28041 Madrid
HUMBOLDT-UNIVERSITAET BERLIN
Germany
Address
Augustenburger Platz 1
13353 Berlin
IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
United Kingdom
Address
Norfolk Place
W2 1PG London
INSTITUT CATALA DE LA SALUT
Spain
Address
Paseo Valle De Hebron 119-129
08035 Barcelona
INSTITUT CATALA DE LA SALUT
Spain
Address
Paseo Valle De Hebron 119-129
08035 Barcelona
INSTITUTE OF HEALTH CARLOS III
Spain
Address
Calle Sinesio Delgardo 12
28020 Madrid
KAROLINSKA INSTITUTE
Sweden
Address
Huddinge University Hospital
141 86 Huddinge
KING'S HEALTHCARE TRUST
United Kingdom
Address
Denmark Hill, King's College Hospital
SE5 9RS London
NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS
Greece
Address
Mikras Asias Street 75
11527 Athens
OSPEDALE SANTA CHIARA DI TRENTO
Italy
Address
Largo Medaglie D'oro
38100 Trento
OUR LADY'S HOSPITAL FOR SICK CHILDREN
Ireland
Address
Crumlin
12 Dublin
PAEDIATRIC HOSPITAL BAMBINO GESU
Italy
Address
Piazza Sant'onofrio 4
00165 Roma
ROYAL HOSPITAL FOR SICK CHILDREN
United Kingdom
Address
Chalmers Crescent 10
EH9 1TS Edinburgh
SALHGRENSKA UNIVERSITY HOSPITAL
Sweden
Address

41685 Goeteborg
SONDURETA HOSPITAL
Spain
Address
Andrea Doria 55
07015 Palma De Mallorca
THE UNIVERSITY OF MILANO
Italy
Address
Via C. Pascal 38
20133 Milano
THE UNIVERSITY OF MILANO
Italy
Address
Via G. Grassi, 74
20157 Milano
UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE 'AMEDEO AVOGADRO'
Italy
Address
Corso Mazzini 18
28100 Novara
UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II
Italy
Address
Via S. Pansini 5
80131 Napoli
UNIVERSITA DEGLI STUDI DI PADOVA
Italy
Address
Via Gustiniani 3
35128 Padova
UNIVERSITA DEGLI STUDI DI PAVIA
Italy
Address
Viale Taramelli 5, Policlinico San Matteo
27100 Pavia
UNIVERSITAT DE BARCELONA
Spain
Address
Pass. Sant Joan De Deu 2
08950 Esplugues De Llobegrat
UNIVERSITY MEDICAL CENTRE UTRECHT
Netherlands
Address
Heidelberglaan 100
3584CX Utrecht
UNIVERSITY OF BOLOGNA
Italy
Address
Via Massarenti 11
40138 Bologna
UNIVERSITY OF CAGLIARI
Italy
Address
Via Ospedale 119
09100 Cagliari
UNIVERSITY OF GENOVA
Italy
Address
Largo G.gaslini 5
16147 Genova
UNIVERSITY OF GENOVA
Italy
Address
Largo R.benzi 10
16132 Genova
UNIVERSITY OF HAMBURG
Germany
Address
Martinistrasse 52
20246 Hamburg
UNIVERSITY OF ROME "LA SAPIENZA"
Italy
Address
Viale Dell'università 37 Policlinico Umberto I
00186 Roma
UNIVERSITY OF TORINO
Italy
Address
Via Ventimiglia 2
10126 Torino (Turin)
UNIVERSITÀ DEGLI STUDI DI TRIESTE
Italy
Address
Via Dell'istria 65/L
34137 Trieste
Università degli Studi di Napoli 'Federico II'
Italy
Address
Corso Umberto I 34
80138 Napoli