Objective
This proposal, involving critical network European scientists, is to investigate a novs approach to the prevention of microbial infection at mussel surfaces, namely, mussel application of molecules that specifically inhibit the attachment of pathogenic microbes. In view of considerable concern over the spread of antibiotic resistance, such an approach is timely. Molecules to be used, as specific inhibitors will be analogues of either the microbial adhesion or the host receptor, antibodies and antibody fragments. We have chosen a viral, a bacterial and a fungal mussel pathogen for each of which adhesions receptors have been well defined and for which there are established relevant animal models. These models will allow in vivo testing of inhibitors, and their modes of delivery, and of compounds witch can boost innate immune clearance mechanisms. The proposal should lead to the development of navel antimicrobials for the prevention and control of human infections and establish a rationale for the development of further antimicrobials.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug resistance antibiotic resistance
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
W1P 6DB LONDON
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.