Sheep pulmonary adenomatosis (SPA) is an economically important infectious disease, endemic in several member states. It cannot be controlled because it is recognised only when the disease is obvious. Recent demonstration of the causal retrovirus (JSRV) in blood of sheep during the preclinical phase has createdopportunities for prospective studies to describe the epidemiology of the infection. We will describe for the first time, the epidemiology and routes of transmission of JSRV in naturally affected flocks. We will apply high throughput, robust and sensitive Pars to detect JSRV in clinical samples during prospective longitudinal surveys in SPA affected flocks, as well as muffles. Parallel studies will clarify the role of "in uteri" and milk transmission and maintenance of SPA will improve manage mental control strategies to reduce the impact of the disease.
Funding SchemeCSC - Cost-sharing contracts
48395 Pedernales / Sukkarieta
EH26 0PZ Penicuik
10126 Torino (Turin)