Objective Hopes of radical malaria control have been thwarted by the emergence and rapid spread of human malarial parasites that are resistant to every common drug available, including chloroquine, quinine, mefloquine, pyrimethamine, cycloguanil and sulfadoxin. To make matters worse, such multi-drug resistant plasmodium falciparum strains acquire resistances to new antimalarial compounds 1000 times more frequently than do wild-type clones, a phenotype called accelerated resistance to multiple drugs (ARMD), Here we propose a genetic cross to identify the genetic deterministic high level chloroquine drug resistance as well as the accelerated-resistance-to-multiple-drugs phenotype. Fields of science medical and health scienceshealth sciencesinfectious diseasesmalariamedical and health sciencesbasic medicinepharmacology and pharmacydrug resistancemultidrug resistance Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-2. - Key action Control of Infectious Diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator UNIVERSITAETSKLINIKUM HEIDELBERG EU contribution No data Address Im Neuenheimer Feld 324 69120 Heidelberg Germany See on map Total cost No data Participants (4) Sort alphabetically Sort by EU Contribution Expand all Collapse all FOUNDATION BIOMEDICAL PRIMATE RESEARCH CENTRE Netherlands EU contribution No data Address 151,Lange Kleiweg 151 2280 GH RIJSWIJK ZH See on map Total cost No data INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution No data Address Boulevard de l'H(pital 91 75643 PARIS See on map Total cost No data STICHTING KATHOLIEKE UNIVERSITEIT Netherlands EU contribution No data Address Geert Grooteplein 24 6500 HB NIJMEGEN See on map Total cost No data UNIVERSIDAD DEL VALLE Colombia EU contribution No data Address Calle 4B # 36-00 CALI See on map Total cost No data
