Objective
The innate immune system provides a fast response against invasion by pathogens and also determines the quality of the adaptive immune responses. Chlamydia, Mycobacterium and Rotavirus species are intracellular pathogens that cause a variety of severe human diseases. Because of the high incidence of these infections world wide, new or improved tools are necessary to reduce the burden that these pathogens pose on public health. We plan to investigate the role of innate immunity in resistance and pathogenesis of Chlamydia, Mycobacterium and Rotavirus infections in patients and animal models. Our long-term goal is to provide, by targeting the innate immune system, a novel vaccine and therapeutic strategy. Specifically we will examine the roles of
a) pathogen recognition by innate immune responses
b) cytokine modulation of innate responses in the outcome of infection with each of the three pathogens.
We will also focus on the identification of human genes responsible for predisposition to disease. Finally, we intend to use innate immune molecules such as cytokines as adjuvants to improve vaccine strategies.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences public health
- medical and health sciences basic medicine immunology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
171 77 Stockholm
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.