Objective
The final objective of this proposal is to develop optimised strategies of DNA vaccination to foot-and-mouth disease (FMD) in sheep and pigs, for potential use as vaccines including those for " emergency" depending on EU policy of FMDV eradication programmes. One of the major advantages of DNA vaccination over current inactivated vaccines is the avoidance of the costly manipulation of infectious virus in high containment facilities and the risk of infection in the animal due to insufficient inactivation. The ways by which the FMDV DNA vaccine strategy will be optimised will include a comparison of the immunogenicity in sheep and pigs of different FMDV antigens, of a new generation of plasmids, of promising adjuvants for DNA vaccines, of parenteral versus nasal routes of administration and of prime-boost regimens. The protocols giving the best immune responses will be used to evaluate protection to FMDV challenge in sheep and pigs.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology virology
- natural sciences biological sciences genetics DNA
- medical and health sciences basic medicine immunology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
78352 JOUY-EN-JOSAS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.