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Content archived on 2024-05-27

Unraveling hcv pathogenicity for the preclinical development of new therapeutic strategies (HEPCVAX)

Objective

The overall objectives of the HepCVax cluster is to identify viral and host mechanisms which are involved in
(I) viral replication and particle formation,
(ii) pathogen city and viral persistence and, based on the knowledge of virus properties as well as virus-host interactions and pathogenesis,
(iii) to identify innovative antiviral and immunotherapeutic strategies capable of inducing a broad and sustained HCV specific cellular-mediated immune responses. All information emerging from the understanding of the HCV genome will be integrated in the first ever-European sequence database dedicated to Hepatitis C virus. The cluster will be subdivided in three component Networks. Whereas HepCVax-PARTIC will concentrate on the molecular and intracellular level of the virus-host interactions through the identification of factors involved in HCV-particles formation, HepCVax.IMPA TH will focus on the interaction between HCV and different arms of the innate and adaptive immune response. HepCVax-PRECLIN will exploit the expected discoveries made by Networks 1 and 2 to develop and test new immunotherapeutic strategies in vitro and in small animal models.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

LEIDEN UNIVERSITY
EU contribution
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Address
Albinusdreef 2
2300 RC LEIDEN
Netherlands

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (15)

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