Skin cancers are among the most common cancers affecting the European population. A viral aetiology is hypothesized and certain Human Papillomaviruses (HPV) is found in skin cancer tissue, but has not been linked to skin cancer in epidemiological studies. AIM: To obtain solid evidence of which known or hitherto unknown viruses that are regularly present in skin cancer and then assess if these viruses are associated with increased risk for development of skin cancer. TASKS: Molecular detection systems with improved ability to detect and quantify skin cancer-associated viruses will be developed and applied to a large series of skin tumours. Serological methods based on virus-like particles will be developed. Population-based age and sex-specific prevalence's and attack rates of infection will be determined. Finally, the virus-specific relative risk for skin cancer will be determined by prospective studies.
Funding SchemeCSC - Cost-sharing contracts
171 76 Stockholm