Objective
This project will combine data from European cohorts of persons with known dates of HIV seroconversion (seroconverters) to assess to what extent transmission with drug resistant HIV impacts on clinical outcome. The individual cohorts have been specifically set up as HIV natural history cohorts and study subjects are followed-up life-long from their initial contact with HIV. Although transmitted drug resistance has been documented, but may be under-estimated if data are not derived from seroconverters, its clinical importance has not been established. In studies of persons with known dates of seroconversion, the numbers included are often small and it is very difficult to draw conclusions, on whether a blunted immunology and virology response to therapy is more likely in someone newly infected with drug resistant virus than someone who is not.
Funding Scheme
CON - Coordination of research actionsCoordinator
W1N 4AL London
United Kingdom
Participants (13)
1105AZ Amsterdam
B9 5SS Birmingham
33076 Bordeaux
33076 Bordeaux
28029 Madrid
00161 Roma
1018 WT Amsterdam
5000 Odense
2300 Koepenhagen
20157 Milano
03550 San Juan De Alicante
W1T 4JF London
50411 Tartu