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Content archived on 2024-05-27

Virological characterisation of primary hiv infection in the concerted action on seroconversion to aids and death in europe (CASCADE VIROLOGY)

Objective

This project will combine data from European cohorts of persons with known dates of HIV seroconversion (seroconverters) to assess to what extent transmission with drug resistant HIV impacts on clinical outcome. The individual cohorts have been specifically set up as HIV natural history cohorts and study subjects are followed-up life-long from their initial contact with HIV. Although transmitted drug resistance has been documented, but may be under-estimated if data are not derived from seroconverters, its clinical importance has not been established. In studies of persons with known dates of seroconversion, the numbers included are often small and it is very difficult to draw conclusions, on whether a blunted immunology and virology response to therapy is more likely in someone newly infected with drug resistant virus than someone who is not.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CON - Coordination of research actions

Coordinator

MEDICAL RESEARCH COUNCIL
EU contribution
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Address
Euston Road, 222
W1N 4AL LONDON
United Kingdom

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (13)

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