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Transcriptional control of t helper cell differentiation

Objective

I propose to analyse the genetic program that controls the development of human helper T cell subsets on a genome-wide scale using microarrays. In particular, I will define the regulation of T-bet and GATA-3 transcription factors and their role in the initiation of The- or The-specific transcriptional cascades.

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

INSTITUT PASTEUR
Address
Rue Du Docteur Roux 25
75724 Paris
France