Transcriptional control of t helper cell differentiation

Objective

I propose to analyse the genetic program that controls the development of human helper T cell subsets on a genome-wide scale using microarrays. In particular, I will define the regulation of T-bet and GATA-3 transcription factors and their role in the initiation of The- or The-specific transcriptional cascades.

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-2. - Key action Control of Infectious Diseases

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

INSTITUT PASTEUR

Address

Rue Du Docteur Roux 25
75724 Paris
France