Ectins will find commercially viable ways to derive conditionally immortalised neural stem cells, identify their key phenotype features, patterns of gene expression and biological activities that predict in vivo efficacy. We shall demonstrate clinical potential, study dosing and cell placement through developing predictive animal models of human neurological disease states. Media formulations will be optimised for long term viability, maintain efficacious properties and minimise toxicity. We shall develop non-invasive magnetic resonance imaging methods to follow the activity of grafted cells in human stroke patients. Scientific innovation at all stages of the programme will ensure future product pipelines.
Funding SchemeCSC - Cost-sharing contracts
W1W 7BS London
CB2 1TN Cambridge