European cell therapy in the nervous system

Objective

Ectins will find commercially viable ways to derive conditionally immortalised neural stem cells, identify their key phenotype features, patterns of gene expression and biological activities that predict in vivo efficacy. We shall demonstrate clinical potential, study dosing and cell placement through developing predictive animal models of human neurological disease states. Media formulations will be optimised for long term viability, maintain efficacious properties and minimise toxicity. We shall develop non-invasive magnetic resonance imaging methods to follow the activity of grafted cells in human stroke patients. Scientific innovation at all stages of the programme will ensure future product pipelines.

Fields of science

• natural sciences › biological sciences › neurobiology
• medical and health sciences › medical biotechnology › cells technologies › stem cells
• medical and health sciences › basic medicine › neurology › stroke
• engineering and technology › medical engineering › diagnostic imaging › magnetic resonance imaging

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-3. - Key action The "Cell factory"

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

RENEURON LIMITED

Address

5-11 Lavington Street
SE1 0NZ London
United Kingdom

Participants (8)

FONDAZIONE CENTRO SAN RAFFAELE DEL MONTE TABOR - ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO

Italy

Address

Via Olgettina 58
20132 Milano

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

Address

Rue De Tolbiac, 101
75654 Paris

KING'S COLLEGE LONDON

United Kingdom

Address

De Crespigny Park, Denmark Hill
SE5 8AF London

Links

LUDWIG INSTITUTE FOR CANCER RESEARCH

United Kingdom

Address

Riding House Street 91
W1W 7BS London

MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

Germany

Address

18 A,am Klopferspitz 18 A
82152 Planegg-martinsried

MEDI-CULT A/S

Denmark

Address

Mollehaven 12
4040 Jyllinge

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

United Kingdom

Address

Trinity Lane, The Old Schools,
CB2 1TN Cambridge

UNIVERSITY OF HELSINKI

Finland

Address

Yliopistonkatu 4
00014 Helsinki