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Content archived on 2024-05-21

Construction of corynebacterium glutamicum strains producing either l-valine or d-pantothenic acid - a rational approach using genome research

Objective

Amino acids and vitamins play an essential role in economic and ecologically sociable animal nutrition in stock farming. Corynebacterium glutamicum has been chosen as a bacterial cell factory to study the biological production of the amino acid L-valise and the vitamin D-antithetic acid by a rational approach using genome research for metabolic engineering. This approach is based on a whole-genome analysis with the principle idea to use genome-wide data and innovative technologies such as DNA chip technology, transcriptomics and polemics. Genetic and metabolic targets will be identified in multi-disciplinary approaches to develop new generations of production strains. Small-scale simulation studies will provide a sound basis for the subsequent industrial scale-up.

Fields of science (EuroSciVoc)

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Topic(s)

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Call for proposal

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Funding Scheme

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CSC - Cost-sharing contracts

Coordinator

UNIVERSITY OF BIELEFELD
EU contribution
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Address
Universitaetstrasse 25
33501 BIELEFELD
Germany

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Total cost

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Participants (12)

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