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Production of natural and recombinant saponins by genetic improvement of wild and under-utilised species of gypsophila.

Objective

Gypsophila is widely cultivated in Europe for its flowers, whereas its roots are milled in the soil, with a high environmental cost. Gypsophila roots contain aspirin complex of high chemical, pharmaceutical and medical interest. Today the raw material for spooning extraction is mainly imported from non-European countries. Moreover, the worldwide sale of plant-derived drugs is growing. For such reason proposal objectives are to optimise the production of Gypsophilasaponins and to expand their market by:
1) developing growing and harvesting systems for selected Gypsophila species,
2) establishing cell lines for in vitroproduction of spooning,
3) bioengineering enzyme activities important in the biosynthesis of specific spooning to produce high value spooning,
4) purifyingsaponins up to monosubstances. By thus providing new products, several Gypsophilawild species and cultivars will acquire high added value enhancing the competitiveness of European industry.

Funding Scheme

EAW - Exploratory awards

Coordinator

AZIENDA AGRICOLA MERISTEMA SRL
Address
Localitá Riaccio
56030 Calcinaia
Italy

Participants (1)

DR. H.SCHMITTMANN GMBH
Germany
Address
Langenhorster Str.30
42551 Velbert