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Biodegradable controlled drug delivery systems for the treatment of brain diseases

Objective

The major objective of the present proposal is to develop new therapeutic strategies for the treatment of brain diseases. The aim is to restore, maintain and improve cell, tissue and organ functions within the Central Nervous System (CNS). Emphasis is on two kinds of diseases: brain cancer and neurodegenerative disorders, namely Parkinson ' s and Huntington ' s Disease. The treatment of CNS diseases is very difficult due to the Blood Brain Barrier, hindering most drugs to reach the brain tissue. Thus, target-specific delivery systems are required. Using a multi-disciplinary approach we will develop new pharmaceutical devices releasing highly potent drugs in a controlled manner into the CNS. The whole range of innovation, from advanced research, through technological development up to in vivo evaluation will be covered. With an industrial company in the consortium, also the economic exploitation of the outcoming scientific results is foreseen.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Address
Rue Andrt Boquel 10
49100 Angers
France

Participants (5)

FREIE UNIVERSITAET BERLIN
Germany
Address
Kelchstrasse 31
12169 Berlin
UNIVERSITAET REGENSBURG
Germany
Address
Universitaetsstrasse 31
93040 Regensburg
UNIVERSITE D'ANGERS
France
Address
Rue Larrey
49033 Angers
UNIVERSITE D'ANGERS
France
Address
Rue Andrt Boquel 10, Bftiment Ibt
49100 Angers
UNIVERSITY OF LONDON
United Kingdom
Address
Malet Street, Senate House
WC1E7HU London