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Regulation of neural gene expression by graded sonic hedgehog signalling

Objective

Using embryonic chick and mouse neural tube and cellular model systems, we aim to identify how a gradient of Sonic Hedgehog signalling controls differential gene expression to direct neuronal subtype identity in the ventral neural tube.

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

MRC National Institute for Medical Research
Address
The Ridgeway Mill Hil
NW7 1AA London
United Kingdom