Skip to main content
Go to the home page of the European Commission (opens in new window)
English English
CORDIS - EU research results
CORDIS
Content archived on 2024-05-21

Demonstrating the applicability of novel indices of immunological tolerance to clinical practice using immunosuppression-free transplant recipients

Objective

Patients who have received transplants generally require life-long immunosuppressive drugs, which are all associated with potentially life- threatening adverse effects. Occasionally, "tolerant" patients have been able to stop these drugs without losing their grafts, but we cannot differentiate them from others in whom stopping these drugs will result in rejection. In this project, specimens will be collected from tolerant patients and used in a series of novel, tests of immunological reactivity which have been developed by the consortium. An adequate number of such rare patients could only be collected from within a very large population, necessitating a collaboration of this size. We predict that this will reveal a tolerant "fingerprint' which can then be used to identify those whose drugs can be stopped and to define drug protocols which can induce tolerance.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

Data not available

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

DEM - Demonstration contracts

Coordinator

CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
EU contribution
No data
Address
Boulevard Jean Monnet 30
44035 NANTES
France

See on map

Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (4)

My booklet 0 0