Objective
One of the major concerns limiting the potential usage of genetically modified crops and organisms in agriculture is the potential risk for lateral gene transfer in the environment. While numerous studies have considered lateral gene transfer into gut bacteria, the transfer into unicellular eukaroytes has been ignored until now. Here we propose that the unique genome organisation of ciliated protozoa, i.e. the presence of an asexual macronucleus with gene-sized mini-chromosomes, makes them ideal bio-monitors for gene transfer events in the gut of farm animals and insects. The telomeric sequences of gut ciliates plus signature sequences in GMO-derived DNA should allow primers to be developed for bulk DNA analysis by PCR and high throughput screening using fluorescence in situ hybridisation and flow cytometry. These transfer events will be compared to historical gene transfer event evaluated by bioinformatical techniques.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology genetic engineering gene therapy
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences microbiology protozoology
- natural sciences biological sciences zoology entomology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
6500 GL NIJMEGEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.