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Content archived on 2024-05-15

Development of methods for predictive toxicity testing with reference to neurotoxic volatile chemicals.

Objective

The present proposal aims at providing innovative tools and more effective methods for mechanism-based risk assessment of neurotoxic compounds. A novel apparatus for the exposure of cell in culture to volatile agents will be developed. In addition selected cell types representing specific molecular neuronal targets for the toxic agents studied (carbon monoxide, hexane and styrene) will be used as in vitro experimental models. The final aim is to find and propose in vitro tests that could reduce the need for animal studies. By investigating a variety of possible end-points and using a multidisciplinary approach, the overall novelty of the project and the likelihood of a major advance in the field are greatly increased.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

KAROLINSKA INSTITUTE
EU contribution
No data
Address
Nobels Vaeg, 13
171 77 STOCKHOLM
Sweden

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (5)

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