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Development of standardised extract for diagnosis/therapy of cypress pollen allergy and selection of less allergenic cypress plants

Objective

Allergic diseases have been increasing in industrialized countries, affecting more than 20% of European population. In particular pollen from Cypresses sop. Plants, frequently used in the pastures in several reforestation programs, is emerging as severe cause of polonaises. Unfortunately the lack of a standardised Cypresses pollen extract for diagnostic use as well as its early period ofimpollination (November -march) makes difficult an exact diagnosis, mistaking allergic symptoms for seasonal illness. Our research project purposes to reach three main goals:
a) to determine the distribution of various Cypresses sop. throughout Mediterranean Europe and their impact onpollinosis;
b) to develop a standardised Cypresses pollen extract for improving diagnosis possibilities and as a needed premise for preparing a therapeutic vaccine;
c) to select Cupressusspp. clones plants with low allergen content and for low pollen production and/or restricted periodof impollination.

Funding Scheme

EAW - Exploratory awards

Coordinator

LOFARMA SPA
Address
Viale Cassala 40
20143 Milano
Italy

Participants (1)

CBF LETI S.A.
Spain
Address
Sol 5
28760 Tres Cantos