Objective Temporal and regional trends of malignant and reproductive disorders have renewed interest in environmental pollutants. Bio persistent organ chlorines (POC) in food are an important source of environmental exposure to xenohormones. The objective of this project is to characterize the impact of dietary Pocks on human fertility and to provide evidence in support of or against the environmental hormone hypothesis. Inuit people in Greenland, Swedish fishermen ' s families and population samples from Poland and Ukraine are selected for studies of time taken to conceive, semen quality and endocrine disruption. The study includes people with documented body burdens of Pocks ranking among the highest in the world. We set out to corroborate or reject that high dietary intake of POC causes delayed time to conception because of impaired spermatogenesis due to disturbed gonad development in prenatal life. The project will contribute scientific knowledge as basis for appropriate assessment and management of risk related to consumption of POC contaminated diet and provide strong evidence in support of or against the hormonal disruption hypothesis. Fields of science social sciencessociologydemographyfertilitymedical and health sciencesclinical medicineobstetricsmedical and health scienceshealth sciencesnutritionnatural scienceschemical sciencesinorganic chemistryhalogens Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-4. - Key action Environment and Health Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator AARHUS KOMMUNEHOSPITAL - AARHUS UNIVERSITY HOSPITAL EU contribution No data Address Noerreborgade 44, Building 2C 8000 C AARHUS C Denmark See on map Total cost No data Participants (5) Sort alphabetically Sort by EU Contribution Expand all Collapse all INTERREGIONAL CENTRE OF CLINICAL GENETICS AND PRENATAL DIAGNOSTICS Ukraine EU contribution No data Address Tobolskaya Street 42a 61072 KHARKIV See on map Total cost No data ITALIAN AGENCY FOR NEW TECHNOLOGY, ENERGY AND THE ENVIRONMENT Italy EU contribution No data Address Via Anguillarese 301 00060 CAPENA See on map Total cost No data LUND UNIVERSITY Sweden EU contribution No data Address University Hospital 221 85 LUND See on map Total cost No data NATIONAL INSTITUTE OF HYGIENE Poland EU contribution No data Address Chocimska 24 00 791 WARSZAWA See on map Total cost No data UNIVERSITY OF MODENA AND REGGIO EMILIA Italy EU contribution No data Address Via Berengario 14 41100 MODENA See on map Total cost No data