Toxicological evaluation of the immune function of pesticide workers

Objective

Most of the human population is exposed to pesticides, which are ubiquitous contaminants of the ecosystem. Little is known about long-term effects consequent to prolonged, low dose-exposure to these compounds. Some laboratory data are available suggesting that prolonged exposure to pesticides may affect the immune system. This project is aimed at investigating immune parameters in subjects occupationally exposed to organ phosphorous or dithiocarbamates. A further aim of the study is the validation of a testing strategy adequate to investigate the immune system of humans exposed to immunotoxicants.

Fields of science

• medical and health sciences › basic medicine › immunology
• natural sciences › biological sciences › ecology › ecosystems

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-4. - Key action Environment and Health

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

NATIONAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENT

Address

Antonie Van Leeuwenhoeklaan 9
3720 BA Bilthoven
Netherlands

Participants (7)

AZIENDA OSPEDALIERA - POLO UNIVERSITARIO L. SACCO

Italy

Address

Via Grassi 74
20157 Milano

MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH

Italy

Address

Villa Camozzi, Via Camozzi, 2
24020 Ranica

NATIONAL CENTRE FOR HYGIENE, MEDICAL ECOLOGY AND NUTRITION

Bulgaria

Address

15,dimitar Nestorov Boulevard 15
1431 Sofia

THE NOFER INSTITUTE OF OCCUPATIONAL MEDICINE

Poland

Address

Teresy Street 8
90 950 Lodz

THE UNIVERSITY OF MILANO

Italy

Address

Via Balzaretti 9
20133 Milano

UNIVERSITY OF KUOPIO

Finland

Address

Harjulantie 1a
70211 Kuopio

UNIVERSITY OF MAASTRICHT

Netherlands

Address

Universiteitssingel 40
6200 MD Maastricht