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Toxicological evaluation of the immune function of pesticide workers

Objective

Most of the human population is exposed to pesticides, which are ubiquitous contaminants of the ecosystem. Little is known about long-term effects consequent to prolonged, low dose-exposure to these compounds. Some laboratory data are available suggesting that prolonged exposure to pesticides may affect the immune system. This project is aimed at investigating immune parameters in subjects occupationally exposed to organ phosphorous or dithiocarbamates. A further aim of the study is the validation of a testing strategy adequate to investigate the immune system of humans exposed to immunotoxicants.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

NATIONAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENT
Address
Antonie Van Leeuwenhoeklaan 9
3720 BA Bilthoven
Netherlands

Participants (7)

AZIENDA OSPEDALIERA - POLO UNIVERSITARIO L. SACCO
Italy
Address
Via Grassi 74
20157 Milano
MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH
Italy
Address
Villa Camozzi, Via Camozzi, 2
24020 Ranica
NATIONAL CENTRE FOR HYGIENE, MEDICAL ECOLOGY AND NUTRITION
Bulgaria
Address
15,Dimitar Nestorov Boulevard 15
1431 Sofia
THE NOFER INSTITUTE OF OCCUPATIONAL MEDICINE
Poland
Address
Teresy Street 8
90 950 Lodz
THE UNIVERSITY OF MILANO
Italy
Address
Via Balzaretti 9
20133 Milano
UNIVERSITY OF KUOPIO
Finland
Address
Harjulantie 1A
70211 Kuopio
UNIVERSITY OF MAASTRICHT
Netherlands
Address
Universiteitssingel 40
6200 MD Maastricht