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Content archived on 2024-05-24

Chemical and biological characterisation of ambient air coarse, fine and ultrafine particles for human health risk assessment in europe

Objective

The coarse (PM_10-2.5) fine (PM_2.5-0.1) and ultra me (PM_0.1) fractions of ambient air PM_10 are sampled with a previously validated High-Volume Cascade Impact or (HVCI) technique in six European countries. The large-capacity samplings in 3+4-day periods provide relatively large PM masses for chemical and biological characterisation of the selected contrasting PM pollution situations. Routine air quality monitoring data and extensive reference PM samplings are used for further physic-chemical and source characterisation of the above PM_10 subtractions. Inorganic analyses of the total elemental content and readily bio available ions and elements are made as well as analyses of elemental and organic carbon, end toxin and PAH compounds. In-vitro tests in human and marine respiratory cells are made to identify the causative characterises and chemical constituents in catatonic, proin ammatory and geotaxis responses. The key findings from in-vitro studies are investigated by exposing healthy and compromised animals intratracheally and by reanalysing previously collected epidemiological data from a panel study among subjects with chronic cardiovascular disease.

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Topic(s)

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Call for proposal

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Funding Scheme

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Coordinator

NATIONAL PUBLIC HEALTH INSTITUTE
EU contribution
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Address
Neulaniementie 4
70701 KUOPIO
Finland

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Total cost

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Participants (3)

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